Mechanism of action Binds to androgen receptors → transcriptional activation → protein synthesis (muscle growth, bone density). Also stimulates erythropoiesis via EPO up‑regulation.
Common side effects Acne, oily skin, scalp hair loss; mood swings; liver strain (elevated ALT/AST); mild increase in LDL; potential erythrocytosis.
Drug interactions Increases CYP3A4 activity → lowers efficacy of drugs metabolized by this enzyme (e.g., statins). May potentiate CNS depressants (benzodiazepines, opioids) due to additive central effects.
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4. What You Should Do
Ask the pharmacist or prescriber if your medication is known to interact with anabolic steroids and whether you should adjust dosing or monitoring.
Oral contraceptives Risk of clotting; may need alternative contraception
Anticoagulants Heightened bleeding risk with steroids
(Use as a checklist when prescribing or reviewing medication regimens.)
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Bottom line: Anabolic steroid users can experience significant drug interactions that affect cardiovascular, metabolic, and endocrine systems. Carefully review all medications—prescription and OTC—and monitor for adverse effects, adjusting therapy proactively to safeguard health.
